Schizophrenia is a psychiatric disorder whose pathophysiology is largely unknown. It has a
heritability of 60-80%, much of which is attributable to common risk alleles, suggesting
genome-wide association studies can inform our understanding of aetiology. Here, in
69,369 people with schizophrenia and 236,642 controls, we report common variant
associations at 270 distinct loci. Using fine-mapping and functional genomic data, we
prioritise 19 genes based on protein-coding or UTR variation, and 130 genes in total as …